Pretto 2025 - Pathways: HALLMARK_E2F_TARGETS

Select pathway
 
 
 
 
Genes in pathway HALLMARK_E2F_TARGETS
 
 
 
 
Depletion pathways
Info
These plots depict the score of all pathways in negative selection against the the raw p-value (using permutation). The selected pathway is highlighted.
Tumor_IgG
 
 
 
 
Tumor_PD1
 
 
 
 
Spleen_IgG
 
 
 
 
Spleen_PD1
 
 
 
 
DL_IgG
 
 
 
 
DL_PD1
 
 
 
 
NDL_IgG
 
 
 
 
NDL_PD1
 
 
 
 
Mets_IgG
 
 
 
 
Mets_PD1
 
 
 
 
Lungs_IgG
 
 
 
 
Lungs_PD1
 
 
 
 
Liver_IgG
 
 
 
 
Liver_PD1
 
 
 
 
Enrichment pathways
Info
These plots depict the score of all pathways in positive selection against the the raw p-value (using permutation). The selected pathway is highlighted.
Tumor_IgG
 
 
 
 
Tumor_PD1
 
 
 
 
Spleen_IgG
 
 
 
 
Spleen_PD1
 
 
 
 
DL_IgG
 
 
 
 
DL_PD1
 
 
 
 
NDL_IgG
 
 
 
 
NDL_PD1
 
 
 
 
Mets_IgG
 
 
 
 
Mets_PD1
 
 
 
 
Lungs_IgG
 
 
 
 
Lungs_PD1
 
 
 
 
Liver_IgG
 
 
 
 
Liver_PD1
 
 
 
 
Gene rank
Info
These plots show the rank of the gene for all genes in the pathway. The gene were ranked by the LFC vs the input for the depicted celltype.
Tumor_IgG
 
 
 
 
Tumor_PD1
 
 
 
 
Spleen_IgG
 
 
 
 
Spleen_PD1
 
 
 
 
DL_IgG
 
 
 
 
DL_PD1
 
 
 
 
NDL_IgG
 
 
 
 
NDL_PD1
 
 
 
 
Mets_IgG
 
 
 
 
Mets_PD1
 
 
 
 
Lungs_IgG
 
 
 
 
Lungs_PD1
 
 
 
 
Liver_IgG
 
 
 
 
Liver_PD1
 
 
 
 
Heatmap

This heatmap shows the average LFC of all genes in the pathway against the input for all celltypes.

Click on any cell for further information.

 
 
 
 
Copyright © 2025 Reina Lab, La Jolla Institute for Immunology, La Jolla, CA 92037